ZytoLight ® SPEC ALK/EML4 TriCheckTM Probe

The ZytoLight SPEC ALK/EML4 TriCheckTM Probe is designed to detect inversions involving the chromosomal region 2p23.1-p23.2 harboring the ALK gene and the chromosomal region 2p21 harboring the EML4 gene. Moreover, using this probe it is possible to discriminate between EML4-ALK inversions and translocations affecting ALK, but not EML4.

ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.


Probe Maps

 

Ordering Information

Prod. No.:Tests¹ (Volume):Intended Use²:
Z-2117-50
5 (50 µl)
CE IVD
Z-2117-200
20 (200 µl)
CE IVD
 

Download Information

 
 
 

1 Using 10 μl probe solution per test.
2 CE IVD only available in certain countries. All other countries research use only!
Please contact your local dealer for more information.

 

is designed to detect inversions involving the chromosomal region 2p23.1-p23.2 harboring the ALK gene and the chromosomal region 2p21 harboring the EML4 gene. Moreover, using this probe it is possible to discriminate between EML4-ALK inversions and translocations affecting ALK, but not EML4.

ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.

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