ZytoLight ® SPEC FGFR3/IGH Dual Color Dual Fusion Probe

The ZytoLight SPEC FGFR3/IGH Dual Color Dual Fusion Probe is designed to detect the translocation t(4;14)(16.3;q32.3) affecting the FGFR3 (fibroblast growth factor receptor 3, a.k.a. JTK4) gene in the chromosomal region 4p16.3 and IGH (immunoglobulin heavy chain locus, a.k.a. IGH@) locus in 14q32.33. FGFR3/IGH translocations are observed in approximately 15-20% of patients with multiple myeloma (MM).


Probe Maps

 

Ordering Information

Prod. No.:Tests¹ (Volume):Intended Use²:
Z-2282-50
5 (50 µl)
CE IVD
 

Download Information

 
 
 

1 Using 10 μl probe solution per test.
2 CE IVD only available in certain countries. All other countries research use only!
Please contact your local dealer for more information.

 

is designed to detect inversions involving the chromosomal region 2p23.1-p23.2 harboring the ALK gene and the chromosomal region 2p21 harboring the EML4 gene. Moreover, using this probe it is possible to discriminate between EML4-ALK inversions and translocations affecting ALK, but not EML4.

ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.

ISO 9001
ISO 13485
AEO
ZytoVision GmbH

LEGAL NOTICE

For ZytoVision products additional information is available, which is only valid outside the United States of America (USA). With this action you confirm that you have read this legal notice, that you agree with the terms of use, and that you are not intending to use the information provided on this website within USA.

COOKIES

This website uses Google Analytics, a web analytics service provided by Google, Inc. (“Google”). Google Analytics uses “cookies”, which are text files placed on your computer, to help the website analyze how users use the site. For more information please read Privacy Policy / Datenschutzrichtlinien.


Accept & Continue