PRODUCTS
ZytoLight ® SPEC ABL2 Dual Color Break Apart Probe
The ZytoLight SPEC ABL2 Dual Color Break Apart Probe is designed to detect rearrangements involving the chromosomal region 1q25.2 harboring the ABL2 gene. The translocation t(1;12)(q25.2;p13.2)involving ABL2 was shown to result in a chimeric protein consisting of the helix-loop-helix (HLH) domain of ETV6 and the TK domain of ABL2. Further ABL2 fusion partners have been identified in patients with Philadelphia chromosome-like ALL, including PAG1, RCSD1, and ZC3HAV1.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Intended Use²: | ||
|---|---|---|---|---|
| Z-2200-50 |
|
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Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
