PRODUCTS
ZytoLight ® SPEC ABL2 Dual Color Break Apart Probe
The ZytoLight ® SPEC ABL2 Dual Color Break Apart Probe is designed to detect rearrangements involving the chromosomal region 1q25.2 harboring the ABL2 gene. The translocation t(1;12)(q25.2;p13.2)involving ABL2 was shown to result in a chimeric protein consisting of the helix-loop-helix (HLH) domain of ETV6 and the TK domain of ABL2. Further ABL2 fusion partners have been identified in patients with Philadelphia chromosome-like ALL, including PAG1, RCSD1, and ZC3HAV1.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Registration Status²: | ||
|---|---|---|---|---|
| Z-2200-50 |
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Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | In vitro diagnostic medical device according to EU directive 98/79/EC. CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
