VisionArray ® MYCO Chip – Fast and Reliable Genotyping

The genus Mycobacterium comprises more than 140 species, which, for the purpose of diagnosis and treatment, has been grouped into three categories: M. tuberculosis complex (MTC), M. leprae, and nontuberculous mycobacteria (NTM). In the WHO European region, approximately 300,000 tuberculosis cases have been notified in 2016. The majority of the Mycobacterium species belongs to the NTM group and many of these bacteria cause life-threatening infections in humans. Pulmonary manifestations account for 80-90% of all NTM-associated diseases and the differentiation between tuberculosis pathogens and NTM is essential for diagnosis and treatment. No standard treatment of NTMs exists. Therefore, a clear distinction between the present species is of highest importance.

VisionArray ® MYCO Chips

VisionArray ® MYCO Chip 1.0

VisionArray MYCO Chip

The VisionArray MYCO Chip 1.0 is intended to be used with a VisionArray Analysis Package for the qualitative detection and identification of PCR amplicons of the genera Mycobacterium, Mycobacteriodes, Mycolicibacillus, Mycolicibacter, and Mycolicibacteriumas well as several additional clinically relevant mycobacterial species that have been produced with the help of the VisionArray MYCO Primer Kit 1.0 or the VisionArray MYCO PreCise Master Mix.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VA-0003-10

10 CE IVD

VA-0003-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® MYCO PreCise Master Mix

PreCise Master Mix

The VisionArray MYCO PreCise Master Mix is a ready to use PCR Master Mix for amplifying ITS and, in case of M. tuberculosis complex, IS6110 region of mycobacterial genomes including but not limited to those detected by the VisionArray MYCO Chip. The VisionArray MYCO PreCise Master Mix contains the VisionArray MYCO Primer Mix 1.0, dNTP/dUTP Solution, the VisionArray PreCise Taq DNA Polymerase, the PreCise Reaction Buffer, PreCise MgCl2, and the VisionArray Uracil-DNA Glycosylase. During PCR, specific sections of the ITS and IS6110 region of the mycobacterial genomes will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray MYCO Chip.

 

Ordering Information

Prod. No.

Tests Intended Use¹

ES-0008-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® MYCO Primer Kit 1.0

MYCO Primer Kit 1.0

The VisionArray MYCO Primer Kit 1.0 is intended to be used for amplifying ITS and, in case of M. tuberculosis complex, IS6110 region of mycobacterial genomes including but not limited to those detected by the VisionArray MYCO Chip. During PCR, specific sections of the ITS and IS6110 region of the mycobacterial genomes will be biotinylated. The hybridization and detection of the amplified sequences are subsequently performed using the VisionArray Detection Kit and the VisionArray MYCO Chip. The VisionArray MYCO Primer Kit 1.0 includes the VisionArray MYCO Primer Mix 1.0 with high sensitivity for all mycobacteria species.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VP-0002-50

50 CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® PreCise Taq DNA Polymerase

PreCise Taq DNA Polymerase

The VisionArray PreCise Taq DNA Polymerase is a high quality heat stable Taq polymerase intended to be used for the specific amplification of a wide range of DNA fragments. The enzyme has hot-start capabilities, reduces false positives, amplifies low-level target sequences, and promotes amplification of a variety of templates. Further on, necessary for successful Mycobacterium genotyping is the use of the VisionArray MYCO Primer Kit 1.0 in combination with the VisionArray Uracil-DNA Glycosylase. Hybridization and detection of the amplified sequences is performed subsequently using the VisionArray Detection Kit and the VisionArray MYCO Chip 1.0.

 

Ordering Information

Prod. No.

Tests Intended Use

VE-0001-100

100 CE IVD
 

Download Information

 
 

VisionArray ® Uracil-DNA Glycosylase

Uracil-DNA Glycosylase

The VisionArray Uracil-DNA Glycosylase is an E. coli derived glycosylase intended to be used to prevent carry-over contaminations from previous reactions. This is based on the principle of substituting dUTPs for dTTPs during PCR. Therefore, the PCR amplicon can be "discriminated" from the initial DNA strand. Incubating the PCR mixture with the UDG enzyme at elevated temperatures under alkaline conditions (during the initial denaturation step) will remove contaminating U-DNA from the sample, thereby, avoiding false positive results.

 

Ordering Information

Prod. No.

Tests Intended Use

VE-0002-100

100 CE IVD
 

Download Information

 
 

VisionArray ® Detection Kit

VisionArray Detection Kit

The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray MYCO Primer Kit 1.0, the VisionArray PreCise Taq DNA Polymerase, the VisionArray Uracil-DNA Glycosylase, and the corresponding VisionArray MYCO Chip. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArray MYCO Chip.

 

Ordering Information

Prod. No.

Tests Intended Use¹

VK-0003-50

50 CE IVD

 

Prod. No.

Product

E-4051-1

Mini Slide Centrifuge  

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Analysis Packages

VisionArray ® Analysis Package MultiScan

VisionArray Analysis Package MultiScan

The VisionArray Analysis Package MultiScan stands for a simple visualization and quick analysis of up to six VisionArray Chips in a single run. The VisionArray Analyzer Software MultiScan can thereby analyze HPV and MYCO specific Chips simultaneously. Only a few minutes will pass from scan to report.

 

Ordering Information

Prod. No.

Intended Use¹

E-4070-1

CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Analysis Package SingleScan

VisionArray Analysis Package SingleScan

The VisionArray Analysis Package SingleScan stands for a simple visualization and a quick analysis of the VisionArray Chip data. The analysis of a chip and the report of the results can be achieved in just a few minutes.

 

Ordering Information

Prod. No.

Intended Use¹

E-4060-1

CE IVD

1 CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

 

Download Information

 
 

VisionArray ® Marketing Materials

 
 
 
 
 
 

 
References:
Griffith DE, et al. (2007) Am J Respir Crit Core Med 175: 367-416.
Gupta RS, et al. (2018) Front Microbiol 9: 67.
Oren A & Carrity GM (2019) Int J Syst Evol Microbiol 69: 597-9.
Perez-Martinez I, et al. (2013) BMC Res Notes 6: 531.
Simons S, et al. (2011) Emerg Infect Dis 17: 343-9.
Tortoli E (2009) Clin Microbiol Infect 15: 906-10.
ISO 9001
ISO 13485
AEO
ZytoVision GmbH

LEGAL NOTICE

For ZytoVision products additional information is available, which is only valid outside the United States of America (USA). With this action you confirm that you have read this legal notice, that you agree with the terms of use, and that you are not intending to use the information provided on this website within USA.


Accept & Continue