Introduction

FlexISH® products are designed for identification of chromosomal aberrations on formalin-fixed, paraffin-embedded (FFPE) specimens by Fluorescence in situ Hybridization (FISH). Using the FlexISH® products gives you the flexibility to choose between a 1-day (2 h hybridization) or a 2-day (overnight hybridization) protocol by adapting the hybridization time just according to your individual needs! 

FlexISH®  brings Flexibility to your FISH

  • FlexISH® maximizes your flexibility in terms of time and laboratory management.
  • Hybridization time can be varied between 2 hours and overnight.
  • With a hybridization temperature of 37°C the FlexISH® protocol is fully compatible with routine workflows in pathology laboratories.

 


Method Description & FlexISH®  Fluorochromes F<em>lex</em>ISH <sup>®</sup> Method Description

The FlexISH® system uses direct-labeled FISH probes. The probes are detected by fluorescence microscopy using appropriate filter sets. Due to an exciter filter, full-spectrum light, emitted by the microscope lamp, is reduced to light of a defined wavelength that specifically excites the fluorophore of the probe. This light is reflected onto the specimen by a dichroic mirror. The fluorophore emits light of longer wavelengths that passes the mirror. Finally, a barrier filter reduces the emitted light to a defined wavelength that can be detected.

Two factors that mainly influence FISH analyses:

Please refer to your local distributor for precise information regarding the suitable filter sets.

 

FlexISH®  Kits – Convenient Solutions

FlexISH® FISH probes are intended to be used with the:

IVDR 2017/746
ISO 9001
ISO 13485
AEO
ZytoVision GmbH

LEGAL NOTICE

For ZytoVision products additional information is available, which is only valid outside the United States of America (USA). With this action you confirm that you have read this legal notice, that you agree with the terms of use, and that you are not intending to use the information provided on this website within USA.


Accept & Continue