ZytoLight ® SPEC ALK Dual Color Break Apart Probe

The ZytoLight ® SPEC ALK Dual Color Break Apart Probe is designed to detect rearrangements involving the ALK gene. ALK translocations are frequently found in anaplastic large cell lymphoma (ALCL), an aggressive non-Hodgkin lymphoma. Additionally, inversions [inv(2)(p21p23)] affecting the ALK gene have been frequently detected in non-small cell lung cancer (NSCLC) and lead to the formation of EML4-ALK fusion transcripts. ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.

Probe Maps


Ordering Information

Prod. No.:Tests¹ (Volume):Registration Status²:
5 (50 µl)
20 (200 µl)

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1 Using 10 μl probe solution per test.
2 In vitro diagnostic medical device according to EU directive 98/79/EC. 
CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

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