ZytoLight ® SPEC RET Dual Color Break Apart Probe

The ZytoLight SPEC RET Dual Color Break Apart Probe is designed to detect translocations involving the chromosomal region 10q11.21 harboring the RET gene observed e.g. in lung adenocarcinoma.

Since in vitro studies showed transforming activity of KIF5B-RET fusions which could be suppressed by a tyrosine kinase inhibitor, it was assumed that the chimeric oncogene might be a promising molecular target for the treatment of lung cancer.


Probe Maps

 

 

Ordering Information

Prod. No.: Tests¹ (Volume): Intended Use²:
Z-2148-50
5 (50 µl)
CE IVD
Z-2148-200
20 (200 µl)
CE IVD
 

Download Information

 
 
 

1 Using 10 μl probe solution per test.
2 CE IVD only available in certain countries. All other countries research use only!
Please contact your local dealer for more information.

 
ISO 9001
ISO 13485
AEO
ZytoVision GmbH

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