MULTI-TARGET DETECTION USING FLUORESCENCE IN SITU HYBRIDIZATION

ZytoLight® system uses direct labeled FISH probes, which eliminate the need to detect the probes with fluorophore-coupled antibodies. ZytoLight® products allow for the detection of genetic aberrations (e.g. translocations, deletions, amplifications and chromosomal aneuploidies). The innovative TriCheckTM probe design enables the user to discriminate three different gene states using just one probe.

BRINGING FLEXIBILITY TO YOUR FISH

FlexISH® products are designed for the identification of genetic aberrations by FISH. Using these products gives you the flexibility to choose between a 1-day or a 2-day FISH protocol according to your laboratory workflow. The unique DistinguISHTM probes allow detecting rearrangements of two independent genes on a single specimen.

FULLY AUTOMATED – REDUCED HANDS-ON TIME

The ZytoMation® probes combine the quality of the ZytoVision probes for Fluorescence in situ Hybridization (FISH) with an automated workflow. They are designed for fully automated FISH to detect genetic aberrations such as translocations and amplifications in FFPE tissue sections on the Leica BONDTM Systems. Before starting the Leica BONDTM System, the Leica BONDTM FISH Kit has to be complemented with the BONDTM Enzyme Pretreatment Kit and the ready-to-use ZytoMation® FISH Probe transferred to the BONDTM Titration Kit.

ICISH PRODUCTS FOR THE DETECTION OF GENETIC ABERRATIONS

ZytoDot® 2CTM products are designed for simultaneous detection of two different genomic targets by chromogenic in situ hybridization (CISH) by using light microscopy. This two-colour system is especially useful for the differentiation of aneuploidies from gene amplifications and the detection of deletions and translocations.

CHROMOGENIC IN SITU HYBRIDIZATION RESULTS IN JUST 4 HOURS

ZytoFast® PLUS products are designed for outstandingly fast detection and discrimination of human pathogen viruses such as human papillomavirus (HPV), Epstein-Barr virus (EBV), and for the determination of lymphocyte clonality by detecting Ig-kappa and Ig-lambda light chain mRNA by chromogenic in situ hybridization (CISH).

EASY TO HANDLE – CONVINCING RESULTS

The VisionArray® products are designed for the qualitative detection of specific DNA sequences by DNA/DNA hybridization on immobilized catcher molecules, which are arranged on a glass chip. The PCR based VisionArray® Chip system was developed for the qualitative detection of a large number of HPV-types and Mycobacteria species. The interpretation of VisionArray® results is exceptionally user-friendly and relies on a VisionArray® Software for automatic analysis of either one chip or up to six chips simultaneously.