BRIGHTER SIGNALS – SUPERIOR BACKGROUND

ZytoLight® system uses directly labeled FISH probes, which eliminate the need to detect the probes with fluorophore-coupled antibodies. The unique ZytoLight® Direct Label System II and ZytoLight® Repeat Subtraction Technique provide improved signal intensity and lead to advanced specificity and less background of all our probes. ZytoLight® products allow for reliable, highly sensitive and specific detection of genetic aberrations (e.g. translocations, deletions, amplifications and chromosomal aneuploidies). The innovative TriCheckTM probe design enables the user to discriminate three different gene states using just one probe.

BRINGING FLEXIBILITY TO YOUR FISH

FlexISH® products are designed for the identification of genetic aberrations by FISH. Using these products gives you the flexibility to choose between a 1-day or a 2-day FISH protocol according to your laboratory workflow. The unique DistinguISHTM probes allow to detect rearrangements of two independent genes on a single specimen, like the FlexISH® ALK/ROS1 DistinguISHTM probe.

FULLY AUTOMATED – REDUCED HANDS-ON TIME

The ZytoMation® probes combine the known high quality of the ZytoVision probes for Fluorescence in situ Hybridization (FISH) with an automated workflow. They are designed for fully automated FISH to detect genetic aberrations such as translocations and amplifications in formalin-fixed, paraffin-embedded tissue sections on the Leica BONDTM Systems. Before starting the Leica BONDTM System, the Leica BONDTM FISH Kit has to be complemented with the BONDTM Enzyme Pretreatment Kit and the ready-to-use ZytoMation® FISH Probe transferred to the BONDTM Titration Kit. The probes can be used in combination with several BONDTM Systems.

IMPROVED SIGNALS – LESS HANDS ON TIME

ZytoDot® 2CTM products are designed to simultaneously detect two different genomic targets by chromogenic in situ hybridization (CISH) by using light microscopy. This two-colour system is especially useful for the differentiation of aneuploidies from gene amplifications and the detection of deletions and translocations.

OUTSTANDINGLY FAST AND SENSITIVE CISH

ZytoFast® PLUS products are designed for outstandingly fast and sensitive detection and discrimination of human pathogen viruses such as human papillomavirus (HPV), Epstein-Barr virus (EBV) and cytomegalovirus (CMV), and for the determination of lymphocyte clonality by detecting Ig-kappa and Ig-lambda light chain mRNA by chromogenic in situ hybridization (CISH).

EASY TO HANDLE – CONVINCING RESULTS

Infections with the human papillomavirus (HPV) are widespread and categorized as one of the main risk factors for the development of cervical intraepithelial neoplasia and invasive cervical carcinomas and play a significant role in the development of head and neck squamous-cell carcinoma. The PCR based VisionArray® HPV Chip system was developed for the qualitative detection of a large number of clinically relevant types of HPV. Interpretation of VisionArray® results is exceptionally user-friendly and relies on the VisionArray® Analyzer Software for automatic analysis.