PRODUCTS
ZytoLight ® SPEC TERC/CEN 3 Dual Color Probe
The ZytoLight SPEC TERC/CEN 3 Dual Color Probe is designed to detect amplifications affecting the chromosomal region 3q26.2 harboring the TERC gene. 3q copy number gains including the TERC gene locus have been found in several epithelial carcinomas such as cervix carcinoma, prostate cancer, non-small cell lung cancer, and lung squamous cell carcinoma.
Probe Maps
Ordering Information
| Prod. No.: | Tests¹ (Volume): | Intended Use²: | ||
|---|---|---|---|---|
| Z-2284-200 |
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Download Information
| 1 | Using 10 μl probe solution per test. |
| 2 | CE IVD only available in certain countries. All other countries research use only! Please contact your local dealer for more information. |
is designed to detect inversions involving the chromosomal region 2p23.1-p23.2 harboring the ALK gene and the chromosomal region 2p21 harboring the EML4 gene. Moreover, using this probe it is possible to discriminate between EML4-ALK inversions and translocations affecting ALK, but not EML4.
ALK kinase targeted therapies may represent a very effective therapeutic strategy in NSCLC patients carrying EML4-ALK rearrangements.
