FlexISH ® IGK/IGL DistinguISHTM Probe

The FlexISH ® IGK/IGL DistinguISHTM Probe is designed to detect rearrangements affecting the chromosomal region 2p11.2 and 22q11.22 harboring the IGK and IGL gene cluster region, respectively. Translocations involving the immunoglobulin genes are recurring events of B-cell oncogenesis. In all of these translocations, an oncogene is activated and overexpressed by juxtaposition to IG regulatory sequences. Burkitt lymphoma is characterized by reciprocal translocations involving the MYC gene and one of the IG loci.

Probe Maps


Ordering Information

Prod. No.:Tests¹ (Volume):Registration Status²:
5 (50 µl)
20 (200 µl)

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1 Using 10 μl probe solution per test.
2 In vitro diagnostic medical device according to EU directive 98/79/EC. 
CE IVD only available in certain countries. All other countries research use only! 
Please contact your local dealer for more information.

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